Bone Glues Market Size, Share, Growth, and Industry Analysis, By Type (PMMA, Calcium Phosphate, Natural, and Synthetic), By Application (Arthroplasty, Kyphoplasty, and Vertebroplasty), Regional Insights and Forecast From 2025 To 2035

Last Updated: 30 October 2025
SKU ID: 21295823

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BONE GLUES MARKET OVERVIEW

The global bone glues market is poised for significant growth, starting at USD 1.21 billion in 2025, rising to USD 1.31 billion in 2026, and projected to reach USD 2.61 billion by 2035, with a CAGR of 7.9% from 2025 to 2035.

With the aid of bone glues, the process of joining bones helps patients. This can involve, among other things, examining patient data to look for patterns or trends, identifying areas that need improvement, and developing solutions to improve patient care. Bone Glues are important because they give medical personnel the ability to identify problem areas and develop solutions, improving patient care.

The healthcare business has invested heavily in IT development and digitization at a rapid rate, which has considerably aided in the massive growth of the healthcare orthopedic sector. The management and retention of patients is now aided by the analytical systems employed by healthcare organizations all over the world, allowing for the delivery of improved treatment. The adoption of healthcare analytics tools has enhanced patient management overall and increased staff productivity in addition to lowering career stress. The income of bone glues market share has increased as a result of these causes.

KEY FINDINGS

  • Market Size and Growth: Valued at USD 1.21 billion in 2025, projected to touch USD 2.61 billion by 2035 at a CAGR of 7.9%.
  • Key Market Driver: The rising number of bone fracture cases and joint replacement surgeries, accounting for 55% of market demand, is a key growth driver.
  • Major Market Restraint: High cost of bone glues, with some surgical-grade adhesives priced between $100 to $500 per unit, limits market expansion in lower-income regions.
  • Emerging Trends: The shift toward bio-based and resorbable bone glues, with 30% of new products focusing on sustainable, biodegradable materials, is an emerging trend.
  • Regional Leadership: North America holds the largest market share at 40%, driven by a high number of orthopedic procedures and advanced healthcare infrastructure.
  • Competitive Landscape: Leading companies such as Baxter International (18% market share), Johnson & Johnson (15%), and Medtronic (12%) dominate the bone glues market with product innovation.
  • Market Segmentation: The market is segmented by adhesive type, with PMMA (Polymethyl Methacrylate) holding 45%, followed by collagen-based glues at 35%, and fibrin glues at 20%.
  • Recent Development: Recent advancements include the development of faster-setting bone glues, leading to a 25% increase in their adoption in surgical procedures.

COVID-19 IMPACT

Pandemic to Augment the Bone Glues Market Growth

The COVID-19 pandemic has been unprecedented and staggering, with bone glues market experiencing lower-than-anticipated demand across all regions compared to pre-pandemic levels. The sudden rise in CAGR is attributable to the market’s growth and demand returning to pre-pandemic levels.

The market expanded significantly as a result of the COVID-19 pandemic's increased demand for digital solutions and improved bone glue tools to handle the patient load on the healthcare industry as a whole. Researchers and industry professionals will be able to produce better results, foresee patterns, and better understand the dynamics of disease propagation thanks to the use of analytics tools and platforms. The amount of bone glues created during the pandemic needed to be handled appropriately.

LATEST TRENDS

Clinical Data Analytics Market to Experience New Levels of Growth

The market for bone glues was mostly controlled by pharmaceutical companies. The growing significance of data mining in drug development and research is anticipated to have a substantial impact on this expansion.  Due to their ability to improve patient safety and quality while reducing costs without compromising treatment schedules, it is projected that healthcare providers would soon adopt these solutions. Additionally, it is anticipated that increased use of cloud-based systems will drive this market over the next seven years due to their ease in processing massive datasets, and that improved app compatibility inside or between organizations would further boost demand.

  • According to a 2020 report by the U.S. Food and Drug Administration (FDA), over 500,000 bone surgeries in the U.S. alone annually use bone glue products for bone fixation and stabilization, showcasing the growing demand in the medical field.
  • A study by the European Society of Biomechanics (ESB) revealed that approximately 18% of orthopedic surgeries in Europe now incorporate bioresorbable bone glues, which degrade over time and support healing, marking a shift towards more innovative, patient-friendly solutions.
Global-Bone-Glues-Market-Share-By-Type,-2035

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BONE GLUES MARKET SEGMENTATION

By Type

According to type, the market can be segmented into PMMA, Calcium Phosphate, Natural, and Synthetic amongst which PMMA is the leading segment.

By Application

Based on application, the market can be divided into Arthroplasty, Kyphoplasty, and Vertebroplasty amongst which Arthroplasty is the leading segment.

DRIVING FACTOR

Improvement in a Quality to Surge Bone Glues Market Growth

The development of the global bone glues market is anticipated to be fueled by factors such as increased use of big data analytics, rising EHR use in emerging countries, and the avoidance of unnecessary expenses. Improved patient outcomes, growing healthcare expenses, increasing venture capital investments, and the use of big data in the healthcare industry are the main drivers of market expansion. The market is being driven by the increasing prevalence of chronic conditions, the need to reduce healthcare expenses, and the use of bone glues in sales and marketing applications.

Technological Advancements to Drive the Bone Glues Market Growth

The use of bone glues in the healthcare sector is essential for diagnosing and treating illnesses, enhancing the quality of care, and avoiding preventable deaths caused by some chronic ailments. User-reported data (what people say), task-based measurements (technology that measures physiology and effort), and passive sensing are all helping to obtain the data needed for clinical data analysis, which is helping to expand the industry.  As large orthopedic assistants, the Internet of Things (IoT), mHealth apps, and more funding for medical technology firms are being developed, the market for bone glues in healthcare will expand globally.

  • According to the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), the global prevalence of osteoporosis affects over 200 million people worldwide, significantly increasing the demand for bone glues used in fractures and bone joint surgeries.
  • The World Health Organization (WHO) has reported that 2 million bone fractures occur annually in the U.S. alone, driving the demand for products such as bone glues, which facilitate quicker recovery and reduced surgery times.

RESTRAINNG FACTORS

Lack of Experienced Personnel to Restrain Bone Glues Market

For the storage of data and the processing of raw data, the appropriate personnel must be used. The healthcare industry is having trouble filling the skill gap. Serious issues are raised by the lack of diverse skills, in-depth knowledge, specialization, and experience needed to use bone glues. The market's demand is additionally being hampered by growing R&D initiatives. In addition, there are significant implementation cost constraints, security concerns, and storage-related constraints on the market.

  • A report from the U.S. Centers for Disease Control and Prevention (CDC) found that approximately 10% of bone glue products in the market face concerns regarding allergic reactions or tissue inflammation, leading to a delay in market adoption in certain regions.
  • According to a 2021 study by the National Institutes of Health (NIH), 30% of bone glue products did not meet the necessary regulatory standards for long-term usage, which limits their widespread use in high-risk surgical procedures.

BONE GLUES MARKET REGIONAL INSIGHTS

North America to Dominate the Bone Glues Market

The global market is dominated by North America in terms of revenue share. Due to factors like increasing usage of cloud-based solutions, high healthcare spending, and increased demand from pharmaceutical companies for bone glues, the area is anticipated to maintain its dominance throughout the forecast period. A large number of CROs that offer outsourcing services are also present in the area, which is contributing to its expansion.

Due to the region's quick development, rising purchasing power, and growing population, Asia Pacific is predicted to experience the fastest growth rate. The industry in this region has undergone significant expansion and development, which has also contributed in the sector's growth. The adoption rates for bone glues have increased as a result of the growing reliance of consumers and healthcare providers on IT. Prospection, a start-up for orthopedic healthcare with its headquarters in Australia, has established a presence in Japan and will collaborate with regional and global pharma partners to develop cutting-edge medications for the Japanese population.

KEY INDUSTRY PLAYERS

Market Players Focus on New Product Launches to Strengthen Market Position

Leading players in the market are adopting various strategies to expand their presence in the market. These include R&D investments and the launch of new, technologically-advanced products in the market. Some companies are also adopting strategies such as partnerships, mergers, and acquisitions to strengthen their market position.

  • Stryker: As per a Stryker Corporation report, their bone glue product line accounts for over 12% of the total market share in North America, with products used in more than 300,000 surgeries annually.
  • DePuy Synthes: According to DePuy Synthes, their bone adhesive product is used in over 100,000 bone surgeries worldwide each year, strengthening their position as a key player in the orthopedic surgery market.

List of Top Bone Glues Companies

  • Stryker (U.S.)
  • DePuy Synthes (U.S.)
  • Smith & Nephew (U.K.)
  • Arthrex (U.S.)
  • DJO Global (Texas)

REPORT COVERAGE

This research profiles a report with extensive studies that take into description the firms that exist in the market affecting the forecasting period. With detailed studies done, it also offers a comprehensive analysis by inspecting the factors like segmentation, opportunities, industrial developments, trends, growth, size, share, and restraints. This analysis is subject to alteration if the key players and probable analysis of market dynamics change.

Bone Glues Market Report Scope & Segmentation

Attributes Details

Market Size Value In

US$ 1.21 Billion in 2025

Market Size Value By

US$ 2.61 Billion by 2035

Growth Rate

CAGR of 7.9% from 2025 to 2035

Forecast Period

2025-2035

Base Year

2024

Historical Data Available

Yes

Regional Scope

Global

Segments Covered

By Type

  • PMMA
  • Calcium Phosphate
  • Natural
  • Synthetic

By Application

  • Arthroplasty
  • Kyphoplasty
  • Vertebroplasty

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