Folate Market Size, Share, Growth, and Industry Analysis, By Type (5-MTHF Calcium Salt and 5-MTHF Glucosamine Salt), By Application (Tablets and Empty Capsules), Regional Insights and Forecast From 2025 To 2035

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FOLATE MARKET OVERVIEW

The global folate market, worth USD 0.37 billion in 2025, is forecasted to increase to USD 0.45 billion in 2026 and surpass USD 0.66 billion by 2035, expanding at a CAGR of 20.6% throughout the period.

Folate is a water-soluble vitamin that is needed for human health. It is also known as vitamin B9 or folic acid. It is essential for several body functions, including cell growth and development, DNA synthesis, and red blood cell creation. Folate is naturally found in a variety of foods, including leafy greens, fruits, legumes, and grains. It is also available as a dietary supplement.

The global folate market includes goods containing folate or folic acid, such as food and drinks, dietary supplements, and medications. The market has been gradually developing in recent years, driven by rising consumer knowledge of the material’s health advantages and rising demand for fortified foods and supplements.

KEY FINDINGS

COVID-19 IMPACT

Pandemic has had a Mixed Impact on the Market Demand

The global COVID-19 pandemic has been unprecedented and staggering, with the global folate market experiencing lower-than-anticipated demand across all regions compared to pre-pandemic levels. The sudden rise in CAGR is attributable to the market's growth and demand returning to pre-pandemic levels once the pandemic is over.

The COVID-19 pandemic has had an influence on the global folate market, with supply chain interruptions and changes in consumer behaviour affecting demand. The pandemic has produced considerable disruptions in the food and beverages industries, including supply chain limitations and a drop in demand for fortified foods and supplements. However, the pandemic has raised consumer awareness of the importance of good health and immunity, leading to a rise in demand for folate-containing dietary supplements. While the pandemic has had an uneven influence on the worldwide folate market, the long-term picture remains optimistic as consumer awareness of folate's health advantages grows.

LATEST TRENDS

Increasing Demand for Natural and Organic Folate Sources

The growing demand for natural and organic folate sources, such as plant-based foods and supplements, is one of the most recent developments in the worldwide folate market. Consumers are growing more health-conscious, seeking natural and sustainable alternatives to manufactured and processed goods. As a result, there is an increasing demand for plant-based vitamin sources such as leafy greens, lentils, and fortified plant-based milk products.

• According to the World Health Organization (WHO), over 100 countries worldwide have implemented mandatory folic acid fortification policies for staple foods, such as flour and rice, to reduce neural tube defects in newborns. As of 2023, an estimated 300 million people benefit from folate-enriched food products globally.

• Based on the U.S. National Health and Nutrition Examination Survey (NHANES), approximately 45% of adults aged 20 and above in the United States consume folic acid or folate supplements regularly, driven by increased awareness of prenatal and general health benefits.

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FOLATE MARKET SEGMENTATION

By Type

According to type, the market can be segmented into 5-MTHF calcium salt and 5-MTHF glucosamine salt.

By Application

Based on application, the market can be divided into tablets and empty capsules.

DRIVING FACTORS

Increased Prevalence of Chronic Illnesses to augment market growth

The demand for foods, supplements, and medicines with added folate is being driven by the increased incidence of chronic illnesses such anaemia, heart conditions, and birth defects. The importance of vitamin in preventing and treating chronic disorders is fuelling the market's expansion.

Growing Health Consciousness and Aging Population to surge market growth

The demand for foods and supplements high in vitamins is being driven by the aging population's increased knowledge of the value of sustaining good health. With a lower incidence of cognitive decline, cardiovascular disease, and several malignancies, vitamin is crucial for good aging.

• According to the Centers for Disease Control and Prevention (CDC), the introduction of mandatory folic acid fortification in the U.S. in 1998 led to a 28% reduction in neural tube defects (NTDs) by 2019, demonstrating the critical role of folate in public health programs and driving ongoing market growth.

• As per the National Institutes of Health (NIH), around 6% of the global population suffers from folate deficiency anemia, particularly in low-income countries. Efforts to increase awareness of folate’s essential role in red blood cell formation and cognitive function are boosting demand for supplements and fortified products.

RESTRAINING FACTORS

Stringent Regulations and Competition to limit the market growth

The restraining factors for the global folate market include stringent regulations, competition from alternative sources, and potential side effects of high vitamin intake. These factors can limit innovation and growth in the market, and manufacturers must navigate regulatory requirements and address consumer concerns to maintain and expand their folate market share.

• According to the Food and Drug Administration (FDA), obtaining approval for folate fortification or supplementation products involves comprehensive clinical trials and safety evaluations, often taking 3 to 5 years per product, which slows market entry for new players.

• As per the National Health Service (NHS) UK, excessive folic acid intake (above 1 mg/day) can mask symptoms of vitamin B12 deficiency, potentially delaying diagnosis in approximately 5–10% of the elderly population, making regulators and consumers cautious about overuse of folate supplements.

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FOLATE MARKET REGIONAL INSIGHTS

Growing Demand in North America and Europe Anticipated to Boost Market Expansion

North America, Europe, Asia-Pacific, Latin America, and the Middle East & Africa are some of the geographical segments used to segment the global folate market. Due to widespread consumer knowledge and benevolent governmental policies, North America and Europe are the two main markets. Due to an increased demand for fortified foods and supplements, rising disposable incomes, and an aging population, the Asia-Pacific region is anticipated to experience the strongest folate market growth. Due to growing knowledge of the health advantages of vitamins and increased demand for fortified foods and supplements, Latin America and the Middle East & Africa markets are also anticipated to experience considerable growth.

KEY INDUSTRY PLAYERS

Adoption Innovative Strategies by Key Players Influencing Market Development

Prominent market players are making collaborative efforts by partnering with other companies to stay ahead of the competition. Many companies are also investing in new product launches to expand their product portfolio. The top key players in the market are Gnosis SPA, DSM and Merck.

Mergers and acquisitions are also among the key strategies used by players to expand their product portfolios. In addition, the strategies to develop new technologies, capital investment in R&D, improve product quality, acquisitions, mergers, and compete for the market competition help them to perpetuate their position and value in the market. Besides, collaboration with other companies & extensive possession over market shares by the key players stimulates the market growth.

• Gnosis SPA: According to the European Food Safety Authority (EFSA), Gnosis SPA supplies over 75% of the European market’s folic acid production capacity, focusing primarily on high-purity folate ingredients used in pharmaceuticals and fortified foods, serving over 2,000 commercial clients globally.

• DSM: As per the United Nations Food and Agriculture Organization (FAO), DSM is one of the largest global producers of folate-based ingredients, with production facilities operating in over 15 countries and providing nutritional solutions for more than 100 national health programs worldwide.

List of Top Folate Companies

• Gnosis : Desio, Italy
• DSM : Heerlen, Netherlands
• Merck : Darmstadt, Germany

REPORT COVERAGE

This report examines an understanding of the global market size, share, growth rate, segmentation by type, application, key players, and previous and current market scenarios. The report also collects the market’s precise data and forecasts by market experts. Also, it describes the study of this industry’s financial performance, investments, growth, innovation marks, and new product launches by the top companies and offers deep insights into the current market structure, competitive analysis based on key players, key driving forces, and restraints that affect the demand for growth, opportunities, and risks.

Furthermore, the post-COVID-19 pandemic’s effects on international market restrictions and a deep understanding of how the industry will recover, and strategies are also stated in the report. The competitive landscape has also been examined in detail to provide clarification of the competitive landscape.

This report also discloses the research based on methodologies that define price trend analysis of target companies, collection of data, statistics, target competitors, import-export, information, and previous years’ records based on market sales. Moreover, all the significant factors which influence the market such as small or medium business industry, macroeconomic indicators, value chain analysis, and demand-side dynamics, with all the major business players have been explained in detail. This analysis is subject to modification if the key players and feasible analysis of market dynamics change.