Heliox Market Size, Share, Growth, and Industry Analysis, By Type (79/21(Helium/Oxygen mixtures), 70/30(Helium/Oxygen mixtures), 60/40(Helium/Oxygen mixtures), 90/10(Helium/Oxygen mixtures), Other) By Application (Medical Uses, Diving Uses) Regional Forecast From 2025 To 2034

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HELIOX MARKET OVERVIEW

The global Heliox Market size stood at USD 30.49 billion in 2025, growing further to USD 36.25 billion by 2034 at an estimated CAGR of 1.94% from 2025 to 2034.

The United States Heliox Market size is projected at USD 10.66453 billion in 2025, the Europe Heliox Market size is projected at USD 9.72551 billion in 2025, and the China Heliox Market size is projected at USD 5.9847 billion in 2025.

The global COVID-19 pandemic has been unprecedented and staggering, with the heliox market experiencing higher-than-anticipated demand across all regions compared to pre-pandemic levels. The sudden rise in CAGR is attributable to the market's growth and demand returning to pre-pandemic levels once the pandemic is over.

Heliox is a breathing gas mixture that is used in certain medical and diving applications. It is composed of a mixture of helium and oxygen gases, with a higher percentage of helium than normal air. The composition of heliox can vary depending on the specific application and intended use. In medical applications, heliox is used to treat respiratory distress in patients with obstructive airway diseases such as asthma, chronic obstructive pulmonary disease (COPD), and respiratory distress syndrome.

The lower density of heliox compared to normal air reduces the effort required for breathing, which can help to improve oxygenation and decrease respiratory distress. In diving applications, heliox is used as a breathing gas for deep diving operations, as it has a lower density and viscosity than normal air. This can reduce the risk of decompression sickness and allow for longer dive times at greater depths.

KEY FINDINGS

COVID-19 IMPACT

Need for Respiratory Support Boosted Market Demand.

COVID-19 had a life changing impact globally. The global heliox market share was significantly affected. The virus had various impacts on different markets. Lockdowns were imposed in several nations. This erratic pandemic caused disruptions on all sorts of businesses. Restrictions tightened during the pandemic due to increasing number of cases. Numerous Industries were affected. However, the market for heliox experienced an increased demand.

Additionally, the pandemic disrupted global supply chains, including the production and distribution of medical gases such as heliox. This further impacted the availability and distribution of heliox, particularly in regions with high demand for respiratory support. However, efforts were made by manufacturers and suppliers to increase production and distribution of heliox to meet the increased demand.

During the pandemic, there was an increased demand for respiratory support for COVID-19 patients, including the use of mechanical ventilators. Heliox was identified as a potential treatment option for COVID-19 patients with respiratory distress, as it can reduce the work of breathing and improve oxygenation. As a result, there was a surge in demand for heliox in some regions, leading to shortages and price increases. However, as the pandemic subsided the global heliox market share is anticipated to grow.

LATEST TRENDS

Neonatal Respiratory Support to Benefit Market Prospects

Heliox is also used in neonatal respiratory support, particularly in premature infants with respiratory distress syndrome. Recent studies have explored the use of heliox in non-invasive ventilation methods such as nasal continuous positive airway pressure (CPAP), which can improve outcomes in preterm infants.

Heliox is still widely used in deep diving applications, particularly in technical diving and commercial diving operations. Recent developments have focused on the use of different gas mixtures to improve decompression profiles and reduce the risk of decompression sickness. These latest developments are anticipated to boost the global heliox market share.

• Clinical concentrations: The 80:20 (≈79/21) heliox blend remains the most commonly ordered clinical mixture; facilities also use 60:40 or 70:30 depending on oxygen need.

• Helium supply metrics: Reported global/industry data show global production in the order of 1.6–1.7×10^8 m³ (2019–2023 average / estimates) with accelerating production from Qatar and other producers.

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HELIOX MARKET SEGMENTATION

By Type

Based on type, the market is divided into 79/21(Helium/Oxygen), 70/30(Helium/Oxygen), and others.

By Application

Based on application, the market is bifurcated into medical uses and diving uses.

DRIVING FACTORS

Consistent R&D to Boost Market Share

There is ongoing research and development in the use and application of heliox, particularly in medical and respiratory therapy. This includes exploring the use of heliox in different respiratory support methods and the development of more efficient production methods. The availability of alternatives to heliox, such as other medical gases or different diving gas mixtures, can also impact the demand for heliox in certain applications.

Critical Applications to Boost Market Size

In diving applications, heliox is often used as a component of different gas mixtures, such as trimix and heliair, to improve decompression profiles and reduce the risk of decompression sickness. Heliox is widely used in deep diving applications, as it has a lower density and viscosity than normal air. This can reduce the risk of decompression sickness and allow for longer dive times at greater depths. Heliox is also commonly used in neonatal respiratory support, particularly in premature infants with respiratory distress syndrome. These factors are anticipated to boost the global heliox market share.

• High disease burden: 262 million people were affected by asthma in 2019 and asthma remains a leading chronic condition; this drives demand for adjunct therapies and respiratory delivery options.

• Critical-care use cases: Randomized/clinical studies document measurable mechanical benefits — e.g., mechanical ventilation with heliox (60/40) reduced respiratory system resistance from 69.1 to 50.2 cmH₂O·L⁻¹·s⁻¹ in one paediatric series.

RESTRAINING FACTORS

High Costs to Hamper Market Share

Heliox is more expensive than normal air or other medical gases, which can be a significant factor in its use and availability, particularly in regions with limited resources. Heliox may not be readily available in all regions or healthcare settings, which can limit its use and availability for medical applications. The use of heliox in diving applications, particularly in deep diving operations, carries inherent risks such as oxygen toxicity and nitrogen narcosis. These factors are anticipated to hamper the global heliox market share.

• Helium supply constraints: U.S. government and geological data show helium inventories and sales moving (U.S. sales ~81 million m³ in 2024), underlining supply-side risk for medical blends.

• Limited high-quality evidence: Systematic reviews and Cochrane analyses note limited or mixed benefits in some indications (e.g., croup trials with 29 infants in a cited Cochrane comparison), constraining guideline adoption.

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HELIOX MARKET REGIONAL INSIGHTS

North America Dominates the Heliox Market

North America is the major shareholder for the global heliox market share. In North America, there is a high prevalence of respiratory diseases such as COPD, asthma, and cystic fibrosis, which are commonly treated with heliox. In addition, the use of heliox in neonatal respiratory support is also widespread in North America. This demand is likely to drive the production and distribution of heliox in the region. Europe is the second major shareholder for the global heliox market share.

KEY INDUSTRY PLAYERS

Key Players Focus on Partnerships to Gain a Competitive Advantage

Prominent market players are making collaborative efforts by partnering with other companies to stay ahead in the competition. Many companies are also investing in new product launches to expand their product portfolio. Mergers and acquisitions are also among the key strategies used by players to expand their product portfolio.

• HangYang: Founded in 1950; the group reports investment in >60 gas companies with total oxygen production capacity reported at >3.2 million Nm³/h.

• Air Products and Chemicals, Inc.: Operates in ~50 countries with about ~19,000 employees working across industrial and medical gas operations.

List of Top Heliox Companies

• HangYang
• Air Products and Chemicals, Inc
• Air Liquide
• TAIYO NIPPON SANSO
• Praxair
• Messer Group
• InfraPro

REPORT COVERAGE

This research profiles a report with extensive studies that take into description of the firms that exist in the market affecting the forecasting period. With detailed studies done, it also offers a comprehensive analysis by inspecting the factors like segmentation, opportunities, industrial developments, trends, growth, size, share, restraints, etc. This analysis is subject to alteration if the key players and probable analysis of market dynamics changes.