Hepatocyte Growth Factor Market Size, Share, Growth, and Industry Growth, By Type (Phase III (Ongoing), Phase II (Approved), Phase II (Ongoing), Phase 1, Preclinical), By Application (Oncology, Cardiovascular, Central Nervous System, Hematological Disorders, Others), Regional Insights and Forecast To 2033

Last Updated: 23 June 2025
SKU ID: 19942559

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HEPATOCYTE GROWTH FACTOR MARKET OVERVIEW

The global hepatocyte growth factor market size was estimated at USD 0.1 billion in 2024, set to expand to USD 1.07 billion by 2033, growing at a CAGR of 30% during the forecast period.

The HGF gene in humans produces the protein known as hepatocyte growth factor (HGF). A cytokine called hepatocyte growth factor controls cell division and migration. Additionally, it encourages angiogenesis and the regeneration of hepatocytes. In 1984, the protein had been found to be a rat hepatocyte mitogenic protein. Since its discovery, substantial research has shown that HGF may have therapeutic benefits for the management of a number of liver, kidney, and lung illnesses. One neurotrophic growth factor with multiple impacts on the brain and nervous system, HGF, is gaining attention.

Growth factors are essential for wound healing and skin regrowth.  Chronic cutaneous ulcers, pressure ulcers, and acute wounds have all been connected to a deficiency in growth factors. The hepatocyte growth factor market and its technique have recently been found to be a viable topical wound-healing technique. Researchers are focusing on creating new products in order to overcome the limits of products that depend upon a single growth factor. As researchers pay more attention to skin rejuvenation and wound healing, possibilities in the hepatocyte growth factor market growth are predicted.

COVID-19 IMPACT

Supply and Isolation Limitations to Deplete Market Advancement 

The abrupt pandemic outbreak had a negative effect on the healthcare industry in fiscal years 2020–21. The hepatocyte growth factor market was shrouded in uncertainty, aggravating the already dire economic situation.

The emerging new reality is made up of complexity, unpredictability, and potential. The market must develop quickly, become robust, and become agile in order to adapt and prosper. Furthermore, new technological developments will make the market to prosper in the coming years.

LATEST TRENDS

Rising Surgical Operations to Stimulate Market Development

The industry is divided into cancer, cardiovascular, the nervous system, hematologic disorders, and others based on the application. Surgical operations using the protein for regenerative purposes, which include bariatric surgery and cosmetic surgery, are included in the others sector. Due to its capacity to accelerate the healing and regeneration processes, the utilization of hepatocyte growth factor in these operations have considerably expanded in recent years. In terms of contribution to revenue, the oncology sector dominated the whole hepatocyte growth factor market in 2014 as a result of rising cancer incidence rates globally and escalating demand for efficient treatment choices.

Hepatocyte Growth Factor Market Share By Application, 2033

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HEPATOCYTE GROWTH FACTOR MARKET SEGMENTATION

By Type

Based on type; the market is divided into phase III (ongoing), phase II (approved), phase II (ongoing), phase 1, preclinical

Phase III (ongoing), is the leading part of the type segment.

By Application

Based on the application; the market is divided into oncology, cardiovascular, central nervous system, haematological disorders, others

Oncology is the leading part of the application segment.

DRIVING FACTORS

Prevalence of Liver Illness to Aid Market Expansion  

The hepatocyte growth factor, another name for Type I, is a protein that controls liver cell development and differentiation. Over the projection period, it is anticipated that the prevalence of liver illnesses and diseases would increase, driving up demand for hepatocyte growth factor.

It performs a variety of tasks including improving cellular adhesion and invasion capacities, suppressing programmed cell death, stimulating cell proliferation, and initiating angiogenesis. As this demographic is more vulnerable to liver ailments and disorders, the increasing number of geriatric consumers is also projected to spur hepatocyte growth factor market share expansion.

 Growing Hormone Releasing Factor to Foster Industry Progress

Somatomedin or growing hormone-releasing factor are other names for type II. The liver is stimulated by this peptide hormone to produce growth hormones that are released into the blood. Growth variables are proteins that regulate a variety of cellular functions in animals ranging from yeast to humans. They are crucial in the regulation of biological functions such cell division, DNA synthesis, and protein biosynthesis.

RESTRAINING FACTORS

Lack of Experienced Personnel to Hinder Market Advancement  

High prices and a dearth of workers with the required abilities are the main causes of the low demand and thus posing a big challenge for the hepatocyte growth factor market.  The lack of qualified individuals working in development and research is another issue. The main causes of the shortage of trained specialists are low pay, limited laboratory training, and difficult tasks.

HEPATOCYTE GROWTH FACTOR MARKET REGIONAL INSIGHTS

Ongoing Improvements in North America to Support Market Advancement  

In terms of percentage of revenue, North America commanded the world hepatocyte growth factor market in 2019. The area is expected to maintain its dominance during the projection period as a result of elements like attractive reimbursement scenarios, rising chronic disease prevalence, and growing awareness of sophisticated medicines. Furthermore, the existence of important producers and suppliers will support the preservation of this regional supremacy.

KEY INDUSTRY PLAYERS

Key Players Focus on Partnerships to Gain a Competitive Advantage

Prominent market players are making collaborative efforts by partnering with other companies to stay ahead of the competition. Many companies are also investing in new product launches to expand their product portfolio. Mergers and acquisitions are also among the key strategies used by players to expand their product portfolios.

The analyst provides a comprehensive picture of the market through the study, synthesis, and summarization of data from various sources, as well as an examination of important variables such as financial gain, sales prices, competition, and promotions. It identifies the key industry influencers and presents various market facets. The information provided is thorough, reliable, and the result of extensive primary and secondary research. The market report provides a comprehensive competitive landscape as well as an in-depth vendor evaluation methodology and analysis based on both qualitative and quantitative studies to accurately forecast market growth.

The reports cover important advances with in market, as well as inorganic and organic growth strategies. Various companies are concentrating on organic business expansion such as product announcements, product approvals, and other things like patents and events. Acquisitions, partnerships, and collaborations were among the inorganic growth strategies observed in the market. The above activities have paved the way for market participants to expand their business and customer base. With the growing demands for filter products in the international market, market participants in the market are expected to benefit from substantial growth opportunities in the near future.

List of Top Hepatocyte Growth Factor Companies

  • ViroMed (India)
  • AnGes MG (Japan)
  • M3 Biotechnology (U.S.)
  • AVEO Pharmaceuticals (U.S.)
  • Molecular Partners (Switzerland)
  • Yooyoung Pharm (South Korea)
  • F-star (U.K.)
  • Galaxy Biotech (U.S.)
  • Kringle Pharma (Japan)

REPORT COVERAGE

This research offers a thorough analysis of the global market, covering all relevant areas. This includes everything from a broad market overview to micro-level information about size of the market, degree of competition, evolution trend, opportunities in the market, important market drivers, and SWOT opportunities and threats. The reader can use the study to influence industry competitiveness and competitive environment strategies to increase potential profit. Additionally, it offers a straightforward framework for assessing and gaining access to the situation of the corporate organization.

In a nutshell, this study should be read by all market participants, traders, academics, analysts, business planners, and anyone else with an interest in the market. The market competitive landscape is another area that the report structure focuses on. This report presents in depth information the share of the market, macroeconomic indicators, product scenario, operation circumstances of the major players, which aids readers in the industry in recognizing the key rivals and better understanding the market's competitive landscape.

Hepatocyte Growth Factor Market Report Scope & Segmentation

Attributes Details

Market Size Value In

US$ 0.1 Billion in 2024

Market Size Value By

US$ 1.07 Billion by 2033

Growth Rate

CAGR of 30% from 2024 to 2033

Forecast Period

2025-2033

Base Year

2024

Historical Data Available

Yes

Regional Scope

Global

Segments Covered

By Type

  • Phase III (Ongoing)
  • Phase II (Approved)
  • Phase II (Ongoing)
  • Phase 1
  • Preclinical

By Application

  • Oncology
  • Cardiovascular
  • Central Nervous System
  • Hematological Disorders
  • Others

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