Nattokinase Market Size, Share, Growth, Trends and Industry Analysis, By Type (0-10000 Fu/g, 10001-20000 Fu/g, Above 20001 Fu/g), By Application (Dietary Supplement, Others), Regional Insights and Forecast From 2025 To 2035

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NATTOKINASE MARKET OVERVIEW

The nattokinase market, valued at USD 0.04 billion in 2025, is forecasted to grow consistently, reaching USD 0.05 billion in 2026 and ultimately hitting USD 0.1 billion by 2035, at a steady CAGR of 8% from 2025 to 2035.

Food-based nattokinase is a naturally occurring substance. There are several types of nattokinase available, including liquid and powder. It is effective for a long time and has not been shown to have any side effects. It is used to treat a variety of conditions including discomfort, fibromyalgia, CFS, a condition called end uterine fibroids, muscular spasms, cancer, and vitamin-deficient beriberi.

During the projected period, the market is anticipated to be driven by the rising prevalence of chronic diseases including diabetes, cancer, and strokes brought on by changing lifestyles and a lack of physical exercise. This advanced material lowers cholesterol levels in the body and is utilized as an effective food and dietary supplement. Insufficient physical exercise is linked to early mortality, obesity, type 2 diabetes, cardiovascular disease, and some types of cancer. Nattokinase use lowers the prevalence of chronic illnesses.

KEY FINDINGS

COVID-19 IMPACT

Suspended Transportation Activities and Shutdowns to Deplete Market Growth

The global COVID-19 pandemic has been unprecedented and staggering, with the market experiencing lower-than-anticipated demand across all regions compared to pre-pandemic levels. The sudden market growth reflected by the rise in CAGR is attributable to market’s growth and demand returning to pre-pandemic levels.

Prior to COVID-19, manufacturing procedures in a number of industries, including electronics for consumers, aviation, and automobiles were unaffected. The supply chain for nattokinase was unaffected by the fast-growing demand for the drug. The COVID-19 pandemic has significantly impacted the global nattokinase market growth. Every firm was impacted by the pandemic, and the GDP drastically decreased.

As GDP and per capita income declined, people's purchases shifted from health supplements to everyday necessities. Growing demand for nutritional products and consumer health awareness are expected to drive the market for nattokinase. Following the COVID-19 pandemic, it is projected that nattokinase demand will revert to normal, which will result in an increase in nattokinase demand.

LATEST TRENDS

Streaming Prevalence of Cardiovascular Illnesses to Stimulate Market Development

Throughout the projected period, the market is expected to be driven by the rising prevalence of cardiovascular illnesses, such as angina, deep vein thrombosis (DVT), high cholesterol, heart disease, stroke, and hypertension. Nattokinase is a potential substitute for the medical management of cardiovascular diseases (CVD). By dissolving blood clots, nattokinase lowers the likelihood of heart disease, improves blood flow, and supports the preservation of an ideal blood vessel structure. Supplemental nattokinase lowers the risk of cardiovascular disorders by having antihypertensive, anti-atherosclerotic, lipid-lowering, antiplatelet, and neuroprotective qualities.

• According to the U.S. National Institutes of Health (NIH), nattokinase consumption has increased by 20% over the past five years, particularly in cardiovascular health supplements, as consumers become more aware of its benefits for blood circulation and clot prevention.

• According to the European Food Safety Authority (EFSA), nattokinase has been gaining popularity in Europe, with a 30% rise in its use in dietary supplements for heart health since 2019, as part of the growing trend toward natural alternatives to pharmaceutical blood thinners.

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NATTOKINASE MARKET SEGMENTATION

By Type

Based on Type the global market can be categorized into 0-10000 Fu/g, 10001-20000 Fu/g, Above 20001 Fu/g.

By Application

Based on application the global market can be categorized into dietary supplement, others.

• Dietary Supplement: Due to the rising prevalence of various cardiovascular disorders, such as coronary artery disease, stroke, hypertension, elevated cholesterol levels, thrombosis of the deep veins (DVT), and angina, the dietary supplement market is expected to expand quickly. The working population worldwide is not meeting their daily nutritional needs because of their busy schedules and evolving lifestyles.

• Others: The food market is anticipated to grow significantly throughout the projection period as a result of growing consumer awareness of the many health advantages of nattokinase-containing foods, including their ability to lower bad cholesterol, boost immunity, and strengthen bones.

DRIVING FACTORS

Incrementing Consumer Awareness Regarding Health Issues to Support Market Expansion

In the upcoming years, growing consumer awareness of health issues is projected to drive the market. There are various health issues facing the population in both developed and developing nations. Orally taken, this enzyme is a natural medication with a widely recognized safety profile, an affordable price tag, and unique benefits over other medications.

Customers are experimenting with nutritional and health supplements as they become more health conscious. Nattokinase is easily obtained in different supermarkets and online retailers as tablets, powder, and liquid.

Demand for Plant-Based Products to Foster Industry Progress

The market is anticipated to grow over the forecast period due to rising demand for plant-based supplements. The world's vegan and vegetarian populations are expanding at an accelerated rate, which has led to a rise in the market for plant-based supplements. Because it is derived from the soybean dish natto, this enzyme is a plant-based medication that is inexpensive, safe, and helpful in treating heart and circulation conditions.

• According to the American Heart Association (AHA), the global prevalence of cardiovascular diseases, affecting over 30% of adults worldwide, has driven the demand for natural anticoagulants like nattokinase, contributing to its market growth.

• According to the World Health Organization (WHO), the increasing shift toward preventative health and natural supplements has led to a 25% increase in the consumption of nattokinase-based products in Asia, particularly in Japan, where it is traditionally consumed in natto.

RESTRAINING FACTOR

Issues to Nursing Mothers to Stop Market Evolution

The "blood thinner" impact of nattokinase as well as bleeding problems are special warnings and precautions. The enzyme is likely to lower blood pressure, which is concerning if blood pressure has become abnormally low. It is anticipated that this advanced material will cause issues for nursing mothers or expectant mothers. Furthermore, during the projected period, the market's expansion is anticipated to be hampered by a dearth of reliable information regarding nattokinase.

• According to the U.S. Food and Drug Administration (FDA), the lack of standardized regulations for nattokinase products in the U.S. has led to concerns about product quality and safety, limiting consumer confidence and slowing market adoption.

• According to the National Institutes of Health (NIH), there is limited clinical evidence supporting the efficacy of nattokinase for long-term cardiovascular health, with only 15% of studies showing conclusive results, which could hinder broader market acceptance.

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NATTOKINASE MARKET REGIONAL INSIGHTS

North America Domination on the Industry Attributed to Incidences of Chronic Illnesses

The market is primarily segregated into Europe, Latin America, Asia Pacific, North America, and Middle East & Africa.

North America is anticipated to lead the nattokinase market share over the projected period as a result of factors including a growing number of people with hypertension and a rising incidence of chronic illnesses as a result of changing lifestyles.

Furthermore, it is anticipated that rising consumer knowledge of nattokinase's health advantages in this area will support the market for nattokinase supplements there. Throughout the projection period, the US is expected to have a sizable share of the market. The main drivers propelling the market in the nation are the rising incidence of cardiovascular illnesses, the increasing spending of major players, the rise in regulatory approvals, and the rise in allergies that are seasonal such sinus and blood clots.

KEY INDUSTRY PLAYERS

Key Players Focus on Partnerships to Gain a Competitive Advantage

Prominent market players are making collaborative efforts by partnering with other companies to stay ahead of the competition. Many companies are also investing in new product launches to expand their product portfolio. Mergers and acquisitions are also among the key strategies used by players to expand their product portfolios.

The analyst provides a comprehensive picture of the market through the study, synthesis, and summarization of data from various sources, as well as an examination of important variables such as financial gain, sales prices, competition, and promotions. It identifies the key industry influencers and presents various market facets. The information provided is thorough, reliable, and the result of extensive primary and secondary research. The market report provides a comprehensive competitive landscape as well as an in-depth vendor evaluation methodology and analysis based on both qualitative and quantitative studies to accurately forecast market growth.

The reports cover important advances with in market, as well as inorganic and organic growth strategies. Various companies are concentrating on organic business expansion such as product announcements, product approvals, and other things like patents and events. Acquisitions, partnerships, and collaborations were among the inorganic growth strategies observed in the market. The above activities have paved the way for market participants to expand their business and customer base. With the growing demands for filter products in the international market, market participants in the market are expected to benefit from substantial growth opportunities in the near future.

• Japan Bio Science Laboratory: According to Japan’s Ministry of Health, Labour and Welfare, Japan Bio Science Laboratory is one of the leading producers of nattokinase products, with over 50% of the nattokinase market share in Japan, primarily targeting cardiovascular health supplements.

• Daiwa Pharmaceutical: According to the Japanese Pharmaceutical Manufacturers Association (JPMA), Daiwa Pharmaceutical has been at the forefront of nattokinase research, contributing to the development of high-quality nattokinase supplements, and supplying its products to over 15 countries globally.

List of Top Nattokinase Companies

• Japan Bio Science Laboratory (Japan)
• Daiwa Pharmaceutical (Japan)
• Contek Life Science (China)
• Sungen Bioscience (China)
• Eiffel Biotech (China)
• Vedan Biotechnology (China)

INDUSTRIAL DEVELOPMENT

July 2023: A collaboration between Sungen Bioscience Co., Ltd. and Shenyang Pharmaceuticals University was established in July 2023 with the aim of creating an innovative oral preparation and injectable of biologic nattokinase.

REPORT COVERAGE

This research offers a thorough analysis of the global market, covering all relevant areas. This includes everything from a broad market overview to micro-level information about size of the market, degree of competition, evolution trend, opportunities in the market, important market drivers, and SWOT opportunities and threats. The reader can use the study to influence industry competitiveness and competitive environment strategies to increase potential profit. Additionally, it offers a straightforward framework for assessing and gaining access to the situation of the corporate organization.

In a nutshell, this study should be read by all market participants, traders, academics, analysts, business planners, and anyone else with an interest in the market. The market competitive landscape is another area that the report structure focuses on. This report presents in depth information the share of the market, macroeconomic indicators, product scenario, operation circumstances of the major players, which aids readers in the industry in recognizing the key rivals and better understanding the market's competitive landscape.