Organs-on-chips (OOC) Market Size, Share, Growth, and Industry Analysis, By Type (Heart, Liver, Lung), By Application (Drug Discovery, Toxicology Research, Other Applications), Regional Insights and Forecast From 2025 To 2033

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Organs-on-chips (OOC) Market Report Overview

The global organs-on-chips (OOC) market size was approximately USD 0.12 billion in 2024 and is projected to grow to USD 2.44 billion by 2033, at a CAGR of 39.9% during the forecast period.

An artificial organ that mimics human organs referred to as "organ-on-chip." It is a multiplex 3D micro-fluidic culture of cells apparatus that stimulates the physiological reactions, mechanisms, and activities of organs. A novel form of in vitro multimodal human creatures has been developed as a result of the ability of researchers to analyze human bodily functions in an organ-specific setting using labs-on-chips (LOCs) and the biology of cells. This chip creates a small passageway for blood and air to travel through many organs, including the heart, liver, brain, intestines, and lungs. These devices are built on a microchip with constantly perfused chambers populated by living cells and configured to stimulate physiology at the level of the tissues and organs. A silicone-based device referred to as "organ-on-chip" is utilized to foster internal organs.

Due to the rising incidence of oncology and increased research and development, the organs-on-chips (OOC) market trends for organs on chips indicate an increase in government activities and investments in drug development. The liver-on-chip model category dominated the market for organs-on-chip, and this pattern is anticipated to persist over the anticipated period (2024-2031). The liver, which is the biggest internal organ within the body of an individual, is crucial to the synthesis and metabolism of many substances, including the metabolism of drugs.

COVID-19 Impact: Expansion of Medical Facility to Advance Market Advancement

The COVID-19 pandemic has been unprecedented and staggering, organs-on-chips (OOC) experiencing higher-than-anticipated demand across all regions compared to pre-pandemic levels. The sudden rise in CAGR is attributable to the market’s growth and demand returning to pre-pandemic levels.

The COVID-19 outbreak is predicted to benefit the market for organs-on-chips (OOC). To expand medical facility capacity for patients with COVID-19 diagnoses, a significant amount of hospitals and clinics around the world underwent restructuring. The fast increase of COVID-19 cases resulted in a potential backlog for non-essential procedures. The lockout caused delays in the production and delivery of critical medical supplies. Organ-on-chip (OOC), however, became a promising technique for the creation of medicines and vaccines that were being researched and tested for the infection during the COVID-19 pandemic. As a result, it had a very favorable effect during the pandemic.

LATEST TRENDS

"Increment in Kidney Applications to Stimulate Market Development "

In addition, the healthcare sector's spike of need for organs-on-chips (OOC) devices is anticipated to drive growth in the worldwide organs-on-chips (OOC) market share. One use for organ-on-chip technology in the medical field is the real-time images, in vitro biochemical analysis, and genetic and metabolic processes of cells that live in a functional tissue. Growth in the organ-on-chip market is being fueled by improvements in the biology of cells, microfabrication, and microfluidics, which have increased the acceptance of organ-on-chips.

The requirement of lung-based organ culture and kidney applications, as well as an increase in requests for drug screening, are what are driving the global market for organs on chips. The organ-on-chip market is anticipated to experience significant growth in the coming years due to the rise in research activities using organ-on-chip devices as an alternative to animal testing for the discovery of new drugs.

Organs-on-chips (OOC) Market Segmentation

• By Type

Based on type; the market is divided into heart, liver, lung, other organs

Heart is the leading part of the type segment.

• By Application

Based on the application; the market is divided into drug discovery, toxicology research, other applications

Drug discovery is the leading part of the application segment.

DRIVING FACTORS

"Growing Market Developments to Aid Market Expansion "

The global market expansion in the anticipated term is being driven by the rising number of market advancements, including product launches, partnerships, mergers, andacquisitionswithin the organs-on-chip (OOC)industry. For instance, Fidia Farmaceutici S.p.A. along with BiomimX S.r.l. established a research partnership in September 2021 with the aim of presenting and involving innovative organs-on-chip-based specialized approaches to the intra-articular medical equipment discovery procedure.

AIM Biotech also released their idenTx 40 Plate in November 2021, a high-throughput organ-on-a-chip approach that enables researchers at biotechnology and pharmaceutical firms to mimic the functionality of human organs and tissues without using animals as test subjects.

"Rising Demand for Substitutes to Animal Testing to Foster Industry Progress"

The worldwide organs-on-chips (OOC) market is expected to increase during the forecast period due to the rising demand for substitutes to animal testing. For instance, over 110 million animals, which includes rats, fish, rabbits, pet dogs, frogs, monkeys, hamsters, rats, cats, guinea pigs, and birds, are killed annually in U.S. laboratories for biological research studies, medical internships, curiosity-driven research, and chemical, pharmaceutical, food, and beauty products testing.

According to a Pew Research Center survey, 52% of American people oppose using animals in scientific research, and other studies show that those who do tolerate animal research do so only because they believe it is necessary for medical progress. The bulk of animal research does not improve human health, and it is questionable how much of an impact animal research has on most medical developments.

RESTRAINING FACTORS

"Exorbitant Price of the technology to Hinder Market Advancement "

However, the exorbitant price of the organs-on-chips (OOC) technology and the fact that organs-on-chip (OOC) technologies is still in its infancy are predicted to impede commercial expansion. Therefore, owing to the above mentioned fact the organs-on-chips (OOC) market growth will deplete.

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Organs-on-chips (OOC) Market Regional Insights

"Rising Research and Developmental Spending in North America to Support Market Advancement"

In the upcoming years, North America is expected to continue to have the fastest-growing organs-on-chip (OOC)market, primarily due to the expansion of the organs-on-chip industry and an increasing need for organ-on-chip models. North Americaorgans-on-chip market shareis also anticipated to rise as a result of factors including rising research and developmental spending and an increase in the outsourcing of these activities.

Additionally, the expansion of local clinical trials is to blame for the market's expansion. In terms of clinical trials undertaken globally, North America is in first place, and numerous clinical studies are now being conducted. For instance, Emulate Inc., a producer of in vitro sophisticated models, unveiled Colon Intestine-Chip in March 2021 for the study of inflammatory intestinal illnesses. The functions of human colon cells will be outlined, the mechanisms driving inflammation will be better understood, and novel therapeutic targets will be made possible by this colon intestinal chip.

KEY INDUSTRY PLAYERS

"Key Players Focus on Partnerships to Gain a Competitive Advantage"

Prominent market players are making collaborative efforts by partnering with other companies to stay ahead of the competition. Many companies are also investing in new product launches to expand their product portfolio. Mergers and acquisitions are also among the key strategies used by players to expand their product portfolios.

The analyst provides a comprehensive picture of the market through the study, synthesis, and summarization of data from various sources, as well as an examination of important variables such as financial gain, sales prices, competition, and promotions. It identifies the key industry influencers and presents various market facets. The information provided is thorough, reliable, and the result of extensive primary and secondary research. Themarket report provides a comprehensive competitive landscape as well as an in-depth vendor evaluation methodology and analysis based on both qualitative and quantitative studies to accurately forecast market growth.

The reports cover important advances with in market, as well as inorganic and organic growth strategies. Various companies are concentrating on organic business expansion such as product announcements, product approvals, and other things like patents and events. Acquisitions, partnerships, and collaborations were among the inorganic growth strategies observed in the market. The above activities have paved the way for market participants to expand their business and customer base. With the growing demands for filter products in the international market, market participants in the market areexpected to benefit from substantial growth opportunities in the near future.

LIST OF TOP ORGANS-ON-CHIPS (OOC) COMPANIES

• AxoSim (U.S.)
• BioIVT (U.S.)
• Emulate (U.S.)
• Elveflow (France)
• MIMETAS (Netherlands)
• Nortis (Switzerland)
• Hurel Corporation (U.S.)
• InSphero (Switzerland)
• Tara Biosystems (U.S.)
• TissUse(U.S.)

REPORT COVERAGE

This research offers a thorough analysis of the global market, covering all relevant areas. This includes everything from a broad market overview to micro-level information about size of the market, degree of competition, evolutiontrend, opportunities in themarket, important market drivers, and SWOTopportunities and threats. The reader can use the study to influence industry competitiveness and competitive environment strategies to increase potential profit. Additionally, it offers a straightforward framework for assessing and gaining access to the situation of the corporate organization.

In a nutshell, this study should be read by all market participants, traders, academics, analysts, business planners, and anyone else with an interest in the market. The market competitive landscape is another area that the report structure focuses on. This report presents in depth information the share of the market, macroeconomic indicators, product scenario, operation circumstances of the major players, which aids readers in the industry in recognizing the key rivals and better understanding the market's competitive landscape.