Oxyclozanide Market Size, Share, Growth, and Industry Growth by Type (Content 98% and Content 99%), By Application (Injectables, Oral Liquids, and Feed Additives), Regional Insights and Forecast From 2025 To 2034

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OXYCLOZANIDE MARKET OVERVIEW

The global Oxyclozanide Market is projected to reach USD 0.04 billion in 2025, steadily progressing to USD 0.1 billion by 2034, with a CAGR of 11.4% from 2025 to 2034.

The United States Oxyclozanide market size is projected at USD 0.015 billion in 2025, followed by Europe at USD 0.013 billion, and China at USD 0.011 billion.

The salisylanilide anthelmintic, oxyclozanide, is used to treat and control fascioliasis in cattle, sheep, and goats. Many oxyclozanide preparations on the market are designed for ruminant use and are combined with roundworm remedies like levamisole or oxfendazole. The uncoupling of oxidative phosphorylation in flukes is the principal mechanism action of oxyclozanide.

Oxyclozanide is available as an oral drench, in combination with levamisole hydrochloride or oxfendazole, or as a powder that can be mixed into the feed. It primarily works in flukes by uncoupling oxidative phosphorylation. For goats and sheep, the recommended dose is 15 mg oxyclozanide/kg bw, and for cattle, the recommended dose is 10 to 15 mg oxyclozanide/kg bw. The use of oxyclozanide has been modified to exclude goat milk and tissues, as well as sheep milk. However, when given in large doses, oxyclozanide can cause severe respiratory problems, salivation, tachycardia, and fever. Increasing application in feed additives will

Key Findings

COVID-19 Impact

Supply Chain Hurdles and Raw Material Unavailability Affected Market Growth

The global COVID-19 pandemic has been unprecedented and staggering, with the oxyclozanide market experiencing lower-than-anticipated demand across all regions compared to pre-pandemic levels. The spike in CAGR is attributable to the oxyclozanide market growth and demand returning to pre-pandemic levels once the pandemic is over.

The pharmaceutical industry is one of the very few industries that witnessed growth during the period of COVID-19. Despite the fact that some aspects of the pharmaceutical industry were impacted, such as the supply chain and the import of active pharmaceutical ingredients, COVID-19 provided some opportunities in the pharmaceutical sector.

Even though the whole pharmaceutical sector had growth, COVID-19 affected oxyclozanide market slightly negatively. The spread of coronavirus necessitated the implementation of lockdown measures in order to contain the virus's spread. This resulted in travel restrictions and supply chain disruptions, affecting product availability on time. Furthermore, the slow growth of the livestock industry impacted product demand.

LATEST TRENDS

Rise in Cattle Farming to Result in Increased Demand for Oxyclozanide

The increasing demand from livestock such as cattle, goats, and sheep, combined with the increase in feed additives in the animal, is driving the growth of the oxyclozanide market. As a result, increased demand for feed additives is expected to drive the market during the forecast period. Increasing veterinary medicine demand is expected to drive significant growth in oxyclozanide during the review period.

The global oxyclozanide market is home to a large number of large, small, and medium-sized businesses. The majority of them are working hard to gain a competitive advantage in the market. To that end, they are investing heavily in research and development in order to develop cutting-edge drugs. To compete with their rivals, a few others are focusing on organic and inorganic strategies such as joint ventures, mergers and acquisitions, collaborations and partnerships, and new product launches.

• According to India’s Department of Animal Husbandry and Dairying, livestock population in India crossed 535 million in the 20th Livestock Census (2019), driving significant demand for anthelmintics like oxyclozanide in cattle, goat, and sheep treatment.

• As per the European Medicines Agency (EMA), oxyclozanide-based flukicide combinations were included in over 240 veterinary medicinal products across Europe by 2023, indicating increasing integration in mixed formulations.

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OXYCLOZANIDE MARKET SEGMENTATION

• By Type

Based on type the market is classified into content 98% and Content 99%. Content 98% segment will lead the global oxyclozanide market share through 2028.

• By Application

Based on application the market is classified into injectables, oral Liquids, and feed Additives.  The injectables segment will dominate the global oxyclozanide market share through 2028.

DRIVING FACTORS

Rise in Usage of Oxyclozanide in Various Applications to Drive the Market Growth

 The rise in usage of oxyclozanide in various forms such as injectables and oral forms is one of the major driving factors of the market. The recent moderate downward trend in product prices will continue in the future which accounts for the huge production and marketing of the drug. Various research activities discovered that the veterinary drug oxyclozanide attacked the cell membrane rather than intracellular pathways, making drug resistance less likely to develop. It was used to treat antibiotic-resistant staphylococcal infections.

Oxyclozanide is commonly used as a feed additive in a variety of disciplines, including cattle, sheep, pig, and other feeds. Another factor expected to drive oxyclozanide market growth in the coming years is increased demand for swine feed.

• According to the Food and Agriculture Organization (FAO), global livestock production is expected to rise by 14% by 2030, with increased fluke infestation cases requiring compounds like oxyclozanide for fascioliasis control.

• As reported by the U.S. Department of Agriculture (USDA), liver fluke infection was identified in 18% of slaughtered cattle samples in 2022, reinforcing the clinical demand for targeted antiparasitic treatment.

RESTRAINING FACTORS

Toxicity of Oxyclozanide to Hamper Market Growth

Several unfavorable factors are hampering the global oxyclozanide market growth. One of the major impediments is toxicity. Depression, loss of appetite, and diarrhea are the most common symptoms of oxyclozanide toxicity in ruminants. The liver is the most severely affected organ. Toxicity symptoms in rats included pallor, increased respiration, lethargy, fecal and urine staining of the perineum, and muzzle staining. Aside from toxicity, oxyclozanide has a number of side effects. At therapeutic doses, oxyclozanide may cause Adverse Drug Reactions (ADRs) similar to the previously described intoxication symptoms, but in a mild and transient form. Another barrier is that oxyclozanide has no specific antidote. Supportive and symptomatic measures are used in treatment. Due to the sheer pharmacodynamic action of oxyclozanide, veterinarians

administer this medication to animals at a lower dosage. However, the availability of other safer alternatives could hamper product demand to some extent.

• According to the Central Drugs Standard Control Organization (CDSCO, India), oxyclozanide showed hepatotoxicity symptoms in over 21% of lab-tested rodent models, limiting its high-dose usage in sensitive animals.

• As per the Veterinary Medicines Directorate (U.K.), oxyclozanide lacks an established antidote, and over 40% of overdose cases require extended symptomatic care, deterring use in some veterinary practices.

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OXYCLOZANIDE MARKET REGIONAL INSIGHTS

Asia Pacific to Dominate Owing to Rise in Cattle Farming

 Asia Pacific leads in the global market since India is home to the majority of the key manufacturers of the market and thereby holds half of the global oxyclozanide market share. Many countries in Asia Pacific including India witnessed a huge expansion in the agriculture industry and the spike in cattle farming also accounts for the demand and growth of the market in these areas. As cattle farming increases, the probability of getting affected with diseases also increases which thereby results in the global oxyclozanide market growth.

Other developing countries in the Middle East & Africa region also hold a notable share in the global market, due to the huge expansion of the agricultural industry throughout the region. The increase in number of infections, especially among cattle will create new opportunities for market players in this region. 

KEY INDUSTRY PLAYERS

Key Players Focus on Partnerships to Gain a Competitive Advantage

Prominent market players are making collaborative efforts by partnering with other companies to stay ahead of the competition. Many companies are also investing in new product launches to expand their product portfolio. Mergers and acquisitions are also among the key strategies used by players to expand their product portfolios.

• Siflon Drugs (India): According to Indian Ministry of Commerce export data, Siflon Drugs exported over 80 metric tons of oxyclozanide APIs in 2023 to over 15 countries, including Vietnam and Bangladesh.

•  Yabang (China): Yabang Group’s veterinary division reported producing 60+ metric tons of oxyclozanide and its combination APIs in 2022, serving both domestic and ASEAN market demands.

List Of Top Oxyclozanide Companies

• Siflon Drugs (India)
• Yabang (China)
• Gharda (India)
• ASCENT PHARMA (U.S.)
• Aarambh Life Science (India)
• ProVentus (India)
• Excel Industries (India)
• Konar Organics (India)
• Neha Pharma (India)
• D. H. Organics (India)
• Neeta Interchem (India)

KEY INDUSTRY DEVELOPMENTS

June 2021: Lasa Supergenerics has expanded its product portfolio with the addition of oxyclozanide. The product is in high demand, and management anticipates a large order book from the start of production. The company already has export approvals for a number of countries, where oxyclozanide would be shipped.

REPORT COVERAGE

In the report, factors affecting the market from both demand and supply are evaluated and market dynamics during the forecast period are also forecasted. Also included in the report is a comprehensive PEST analysis of countries, which assesses the governmental, financial, and shared factors influencing their markets. Apart from all of these, the report also provides drivers, restraints, opportunities, and future trends.