Solid Phase Extraction (SPE) System Market Size, Share, Growth, And Industry Analysis, By Type (Single Channel and Multi-Channel), By Application (Food, Pharmaceuticals, and Others), Regional Forecast To 2034

• 

  Request a Free sample to learn more about this report

SOLID PHASE EXTRACTION SPE SYSTEM MARKET OVERVIEW

The global solid phase extraction spe system market size was valued at approximately USD 0.58 billion in 2025 and is expected to reach USD 0.87 billion by 2034, growing at a compound annual growth rate (CAGR) of about 4.75% from 2025 to 2034.

Solid-phase extraction (SPE) is stated to be the method for sample preparation used for segregate types in the sample or to clean up the sample previous to the investigation. Some of the noticeable knowledge comprises Filtration, Protein Precipitation, Equilibrium dialysis/ ultrafiltration, and Liquid Extraction among others. Sample research has enlarged enormous significance by the investigators in the chromatographic investigation, as the polluted or dilute sample may have incorrect or misleading consequences.

KEY FINDINGS

COVID-19 IMPACT

 Pandemic Improved Market Demand

The COVID-19 pandemic has crushed the R&D activities and the continuing scientific trials. Additionally, R&D labs were operational below 50% of their usual capacity owing to the COVID-19 limitations and supply chain disturbances. Though, the pandemic has improved R&D efforts in the direction of concluding a cure for COVID-19. SPE is used for sample preparation before using the sample for quantification using diverse methods.

LATEST TRENDS

Growing Use of SPE to Fuel Market Growth

The growing usage of SPE consumables, demand for high-throughput sample examination necessities along with LC-MS-MS methods, and liquid chromatography-mass spectrometry (LC-MS) are some of the foremost features that contribute to the solid phase extraction (SPE) system market growth. The expansion of this market is largely credited to the growing use of SPE consumables across the pharmaceutical segment. Cumulative demand for high-throughput sample analysis requirements along with LC-MS-MS methods and liquid chromatography-mass spectrometry (LC-MS) has strapped the demand for the SPE consumable across the pharmaceutical sector.

• According to the U.S. EPA, Methods 533 and 537.1 together support measurement of 29 PFAS in drinking water, driving greater use of SPE for environmental monitoring.

• sub-µL to low-µL elution volumes: Microelution SPE formats now deliver elution volumes as low as 20 µL (microelution plates) and support 96-well high-throughput workflows, enabling direct injection without dry-down.

Request a Free sample to learn more about this report

SOLID PHASE EXTRACTION SPE SYSTEM MARKET SEGMENTATION

By Type Analysis

According to type, the market can be segmented into Single Channel and Multi-Channel.

By Application Analysis

Based on application, the market can be divided into Food, Pharmaceuticals, and Others.

DRIVING FACTORS

Technological Development to Stimulate Market Demand

The solid phase extraction (SPE) system market has observed numerous technological developments to light the requirements of biotechnology and biopharmaceutical companies, food and beverage, chemical, semiconductor industries, and environmental testing. These developments have controlled the progress of miniaturized, automated, and computerized systems. These technological developments have augmented the suitability and ease of use of SPE devices. Technical expansion and automation are predicted to increase further in the future, enhancing the growth of the solid phase extraction (SPE) system market. The global solid phase extraction market is rising due to the cumulative technical expansion in product features. 

• U.S. EPA methods 533 and 537.1 were approved for UCMR-5 (2023–2025) and for the PFAS NPDWR, creating mandated monitoring windows (e.g., 2023–2025 UCMR period) and increased lab demand for SPE-based sample prep. According to EPA guidance, these methods are required for compliance monitoring.

• Vendor/technical studies show automation can cut SPE processing time substantially (example: a published case reported a 33% reduction in processing time for 96 samples when automating SPE vs manual processing). This time saving accelerates throughput for large sample panels

Rising Investments to Boost Market Growth

The increasing demand for biological fluid tests owing to the growing health connected concerns and rush in the level of funds in academics and life sciences are the main issues prompting the development of the market. Moreover, development in generics and CROs, rising investments linked with the automation segment and technological development in instrumentation are the motivating factors quickening the growth of the market.

RESTRAINING FACTORS

Government Policies to Restrict Market Expansion

Altering government guidelines and protocols for medical tools manufacturing and delivery or exports are some other factors restraining market development. Government guidelines for medical tools and products are varied with every country.

• EPA method LCMRLs (single-lab) for PFAS under 537.1 range from ~0.5 to 6.3 ng/L for different analytes; meeting these low ng/L reporting limits raises instrumentation and method-validation burdens for labs.

• The PFAS NPDWR requires state laboratory certification programs — EPA notes all primacy states will establish PFAS lab certification programs, which increases compliance overhead (staffing/QA) for labs performing SPE-based PFAS testing.

• Request a Free sample to learn more about this report

•  

SOLID PHASE EXTRACTION SPE SYSTEM MARKET REGIONAL INSIGHTS

Upsurge in the Biotechnology to Flourish Market in North America

North America holds the biggest solid phase extraction (SPE) system market share to display its supremacy in the coming years. This can be credited to an upsurge in biotechnology and pharmaceutical corporations, augmented R&D activities, attention of the prominent players, and accessibility of the most current methods and tools for drug finding investigation.

Asia-Pacific is anticipated to have a sizable market share. This is owing to the increasing demand from several end-users. The foremost aspect attributing to this development comprises the modern advancement in arrangement, developing financial situations, growing investment in biotechnology, and pharmaceutical research administrations in the emerging countries. 

KEY INDUSTRY PLAYERS

KEY PLAYERS FOCUS ON PROTECTING THE ENVIRONMENT

Prominent market players are making collaborative efforts by partnering with other companies to stay ahead of the competition. Many companies are also investing in new product launches to expand their product portfolio. Mergers and acquisitions are also among the key strategies used by players to expand their product portfolios.

• PromoChrom: PromoChrom’s SPE-03 automated SPE system processes up to 8 samples in parallel per run.

• Merck (Merck KGaA / Chromabond): Merck (Chromabond SPE range) offers SPE columns such as 6 mL / 1000 mg CHROMABOND C18 cartridges; Merck’s corporate history dates to 1668

List of Top Solid Phase Extraction Spe System Companies

• PromoChrom (Canada)
• Merck (U.S.)
• Thermo Fisher (U.S.)
• Aurora (U.S.)
• Agilient (U.S.)
• FMS (India)
• PerkinElmer (U.S.)
• Gilson (U.S.)
• Knauer (Germany)
• Waters (U.S.)
• Biotage (U.K.)

REPORT COVERAGE

The report brings together extensive research on the qualitative and quantitative factors affecting the market. It gives an overall macro and micro view of the industry. This research profiles a report with extensive studies on the market that describe the firms affecting the forecasting period. Detailed studies also offer a comprehensive analysis by inspecting factors like segmentation, opportunities, industrial developments, trends, growth, size, share, restraints, etc.