Tris (hydroxymethyl) Aminomethane Market Size, Share, Growth, and Industry Growth by Type (Industrial Grade, Standard Grade and Ultra-Pure Grade) By Application (Biological Buffer, Pharmaceutical Intermediates and Others), Regional Insights, and Forecast from 2023 to 2030

Updated On: 13 November 2023

Tris (hydroxymethyl) Aminomethane Market REPORT OVERVIEW

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The Tris (hydroxymethyl) Aminomethane Market size is expected to grow USD 394.6 million in 2022 to USD 1476 Million by 2028 at a Compound Annual Growth (CAGR) of 24.6% from 2022 to 2028.

Tris(hydroxymethyl)aminomethane, commonly abbreviated as Tris or THAM, is a chemical compound with the molecular formula C4H11NO3. It is a white, crystalline, water-soluble solid that is commonly used as a biological buffer. Tris is a tertiary amine with three hydroxymethyl groups (-CH2OH) attached to the nitrogen atom. The amine group (-NH2) is located at the end of an alkyl chain (-CH2-) that is attached to the nitrogen atom. The presence of these hydroxyl and amine groups allows Tris to act as a buffer, helping to maintain a stable pH in biological and biochemical systems. Tris is commonly used as a buffer in biochemical and molecular biology applications, such as electrophoresis, DNA sequencing, and protein purification. It has a pKa value of 8.1, which means that it is an effective buffer in the pH range of 7.0 to 9.2.

Tris is also used in the formulation of various consumer products, such as shampoos and conditioners, and in the production of some pharmaceuticals. However, it is important to handle Tris with care, as it can be irritating to the eyes, skin, and respiratory system. 

COVID-19 Impact: The Disruption of the Supply Chain Had an Effect on Market Growth 

The pandemic has disrupted supply chains and manufacturing operations, leading to shortages and delays in the production and distribution of Tris and other chemicals. This has resulted in increased prices for some chemicals, including Tris, and challenges for researchers and industries that rely on these chemicals for their work. In addition, the COVID-19 pandemic has increased demand for Tris and other biochemical reagents and buffers that are used in research related to the virus. This has created additional challenges for researchers who are trying to obtain these chemicals for their studies, as well as for manufacturers who are trying to meet the increased demand.

Overall, the COVID-19 pandemic has had a significant impact on the availability and cost of Tris and other chemicals, which has affected research and industry operations in various ways. 

LATEST TRENDS

"Tris has been Widely Employed as a Buffer in Numerous Biochemical Applications to Promote Market Expansion "

Tris has been widely used as a buffer in various biological and biochemical applications, including electrophoresis, protein purification, and molecular biology techniques such as PCR and DNA sequencing. As a result, the demand for Tris has been steady over the years, and it is considered a staple chemical in many research laboratories and industries. There has been a growing interest in the development of new buffer systems that offer improved performance over traditional buffers such as Tris.   

Tris (hydroxymethyl) Aminomethane Market Segmentation

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• By Type Analysis

By type, the tris (hydroxymethyl) aminomethane market is segmented into industrial grade, standard grade, and ultra-pure grade.

The industrial grade segment will dominate the tris (hydroxymethyl) aminomethane market in the coming years. 

• By Application Analysis

Based on applications, the tris (hydroxymethyl) aminomethane markets are biological buffer, pharmaceutical intermediates, and others.  

The biological buffer use segment will lead the global share through 2028. 

DRIVING FACTORS

"pH Stability and Biocompatibility will Accelerate Market Expansion"

Tris has a pKa value of 8.1, which makes it an effective buffer in the pH range of 7.0 to 9.2. This makes Tris a popular choice for many biological and biochemical applications that require a stable pH environment. Tris is relatively non-toxic and biocompatible, making it an ideal buffer for use in many biological and biomedical applications, such as protein purification, DNA sequencing, and cell culture.  

"Molecular Biology Techniques to Support Market Demand  "

Tris is a versatile buffer that can be used in a wide range of applications. It is commonly used in electrophoresis, PCR, and other molecular biology techniques. Tris is readily available from many suppliers and is relatively inexpensive compared to other biological buffers. Tris has been used as a biological buffer for many years and has a well-established track record of use in research and industry. This has led to widespread adoption and acceptance of Tris as a reliable and effective buffer.  

RESTRAINING FACTORS

"The pH Limits and Interference with Some Assays will Limit Market Expansion  "

Although Tris is an effective buffer in the pH range of 7.0 to 9.2, it may not be suitable for applications that require a different pH range. For example, some enzymatic reactions require a pH outside of this range and may require a different buffer system. Tris may interfere with some biochemical assays, such as enzyme-linked immunosorbent assays (ELISAs), due to its inherent absorbance properties. In these cases, alternative buffers may be required.

Tris (hydroxymethyl) Aminomethane Market REGIONAL INSIGHTS

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"North American to Grow at the Highest Tris (Hydroxymethyl) Aminomethane Market Share During the Forecast Period   "

North America is the dominating market for tris (hydroxymethyl) aminomethane, with being the largest consumer due to the presence of a large number of biotechnology and pharmaceutical companies, academic and research institutions. Tris is commonly used in these industries for various applications such as protein purification, electrophoresis, and PCR. Additionally, the growing research and development activities in the region are expected to boost the demand for tris (hydroxymethyl) aminomethane market in the coming years.

The Asia Pacific region is expected to witness significant growth in the demand for tris (hydroxymethyl) aminomethane due to the increasing investment in the biotech and pharmaceutical industries, the growing research and development activities, and the rising demand for high-quality healthcare products. Moreover, the increasing awareness about the benefits of Tris in various biological and biochemical applications is also expected to boost its demand in the region.  

KEY INDUSTRY PLAYERS

"Key Players Focus on Partnerships to Gain a Competitive Advantage "

Prominent market players are making collaborative efforts by partnering with other companies to stay ahead in the competition. Many companies are also investing in new product launches to expand their product portfolio. Mergers and acquisitions are also among the key strategies used by players to expand their product portfolio. 

List of Market Players Profiled

• Suzhou Yacoo Science (China) 
• ANGUS Chemical (U.S.)
• Jiangsu Tianjiayi Chemical (China)
• Merck (Germany)
• Biosynth Carbosynth (Switzerland)
• Nacalai Tesque (Japan)
• Apollo Scientific (UK.)
• ITW Reagents (U.S.)
• Tokyo Chemical Industry (Japan)
• Guangdong Guanghua Sci-Tech (China)
• Hunan Yunbang Bio-pharmaceutical (China)
• Yeasen Biotechnology (Shanghai) (China)
• Beyotime Biotechnology (China)
• Nanjing Search Biotech (China)
• Ranjeck Technology (China)
• Shangqiu Tengfei Biotechnology (China)
• Hubei New De Sheng Material Science and Technology (China)
• Changzhou Welton Chemical (China)
• Anhui Meisenbao Chemical (China)

REPORT COVERAGE

The market research study examines the worldwide market in detail, focusing on important elements such as leading players, product/services, or type, and leading end-use applications. Aside from that, the research analyses major advancements and provides insights into lighting market trends. In addition to the causes indicated above, the paper includes several other factors that have contributed to recent tris (hydroxymethyl) aminomethane market growth in some regions.