Yellow Fever Vaccines Market Size, Share, Growth, and Industry Analysis by Type (Institonal Contributions, Private Purchases & Others), By Application (Routine Immunization, Travelers & Others), Regional Insights and Forecast From 2025 To 2035

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YELLOW FEVER VACCINES MARKET OVERVIEW

The global yellow fever vaccines market size stood at USD 0.16 billion in 2025 and is projected to reach USD 0.17 billion in 2026, growing further to USD 0.23 billion by 2035 at an estimated CAGR of 4.2% from 2025 to 2035.

Yellow fever is a viral ailment spread by mosquitoes in some regions of Africa and South America that can be prevented with the yellow fever vaccination. Yellow fever is most frequently prevented with a live attenuated virus vaccination. The 17D strain of the yellow fever virus, which is present in it in attenuated form, stimulates the immune system without really producing the illness. One injection of the vaccine is used to give it. Although it is less frequent, an inactivated yellow fever vaccination is occasionally administered. This kind contains inactive virus particles and calls for numerous doses to provide complete immunity.

The live attenuated vaccination typically only requires one dosage to produce long-lasting immunity. To preserve immunity, several nations, however, mandate booster doses after a set amount of time. The live attenuated vaccine frequently offers lifetime protection with just one dosage. However, those who continue to be at danger of exposure can benefit from booster doses. Mild fever, headaches, and muscle soreness are typical adverse reactions to the vaccination. Rarely do allergies cause severe reactions.

KEY FINDINGS

COVID-19 IMPACT

Industry Shutdown Causes Market Distortion

The global COVID-19 pandemic has been unprecedented and staggering, with yellow fever vaccines industry experiencing higher-than-anticipated demand across all regions compared to pre-pandemic levels. The sudden rise in CAGR is attributable to the market's growth and demand returning to pre-pandemic levels once the pandemic is over.

The COVID-19 outbreak caused problems for manufacturers of healthcare materials, including unstable markets, a drop in customer confidence, and difficulties with import and export commerce. The sourcing of raw materials, packaging, and distribution are all parts of the global supply chain. Due to lockdowns, moving commodities, labels, and other items has become difficult. In addition to having an immediate influence on markets, supply chains, supply and demand, and all of these other things, it also had a financial impact on the markets for healthcare. The pandemic altered the dynamics of the industry, compelling organizations to redesign every aspect of their operational frameworks in order to preserve stability amidst the disturbances. Aside from that, the companies' business operations have been affected by the outbreak, which has an effect on the overall healthcare industry. This has partially impacted the yellow fever vaccines industry.

LATEST TRENDS

Endemic Zones to Boost the Market Growth

Expanding endemic zones for yellow fever can have significant implications for the market. A larger population is in danger of getting yellow fever when endemic zones spread out. As more individuals, including tourists, locals, and healthcare professionals, seek immunization for protection, this often results in an increase in demand for yellow fever vaccines. It can be difficult to meet the increasing demand for these vaccines in newly impacted areas. To provide sufficient doses of vaccine to impacted areas, vaccine producers may need to increase production, which can involve time and money. It is essential to make sure that vaccines go to the populations that need them and the newly endemic areas. To reach remote or underserved areas, this may entail enhancing distribution networks, storage facilities, and vaccination campaigns. Thus, a key trend that is opening up potential for the industry to grow is the expanding endemic zones. These new developments are mostly to blame for the market's overall growth.

• According to the World Health Organization (WHO), yellow fever vaccination coverage in endemic African nations increased to 48% in 2023, reflecting the trend of expanding immunization campaigns.

• The U.S. CDC reported that over 9 million international travelers sought yellow fever vaccination certificates in 2022, highlighting rising demand in travel medicine.

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YELLOW FEVER VACCINES MARKET SEGMENTATION 

By Type

Based on type, the market is classified into Institonal Contributions, Private Purchases & Others.

By Application

Based on the market is categorized into Routine Immunization, Travelers & Others.

DRIVING FACTORS

International Travel that Gives the Market Extra Boost

The yellow fever vaccines industry is significantly impacted by international travel. As a requirement for entry, certain nations and areas with a history of yellow fever demand confirmation of immunization. The vaccination and an International Certificate of Vaccination or Prophylaxis (ICVP) are required of visitors who intend to visit certain regions. Unvaccinated travelers may get the virus in locations where it is endemic and then spread it to areas where it is not endemic through mosquitoes. Yellow fever is a mosquito-borne illness. Travelers should be required to receive a vaccination in order to stop the disease from spreading to other places. As a result, the growth, and the increasing international travel will boost the market. It will contribute to the expansion of the healthcare industry and it will improve the overall yellow fever vaccines market growth.

Technological Advancement to Encourage Market Expansion

The development of technology is a factor that is accelerating market expansion. More stable vaccination formulations were being developed by researchers. This includes initiatives to make the vaccine available in more remote regions by doing away with the necessity for a cold chain during delivery and storage. The use of cell culture-based techniques as novel vaccine production techniques was being investigated. With the help of these techniques, vaccine production will be more productive and less dependent on egg-based procedures. To improve the immune response, vaccines are given adjuvants. New adjuvants were being looked into by researchers to perhaps increase the efficacy of yellow fever vaccines. As a result, these factors are collectively promoting market expansion, increasing company revenues. As a result, above mentioned factors will help the market to boost.

• According to WHO data, yellow fever causes 30,000–60,000 deaths annually worldwide, driving strong government-backed vaccination programs.

• The International Air Transport Association (IATA) highlighted that 1.4 billion global passengers in 2023 traveled across regions requiring proof of vaccination, boosting vaccine uptake.

RESTRAINING FACTORS

Supply Chain Management to Impede Market Expansion

Supply chain management is the impediment to market expansion. It can be difficult to maintain a steady supply chain for vaccines, particularly in areas with poor infrastructure. In some places, it can be logistically difficult to store and transport these vaccines using a cold chain. These limitations limit the market's overall growth. This may be a significant issue limiting market expansion. If this problem is fixed, the market will start to grow right away.

• The WHO noted that global yellow fever vaccine stockpiles reached only 35 million doses in 2022, while over 80 million doses were needed, showing a supply gap.

• According to UNICEF, distribution challenges meant that over 25% of rural clinics in Africa faced vaccine shortages in 2023, limiting access.

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YELLOW FEVER VACCINES MARKET REGIONAL INSIGHTS

North America Dominating the Market Across the Globe

The market for yellow fever vaccines in North America has benefited from the region's expanding industrial development, and various driving factors which has increased the potential sectors as this region is the largest user of the product. The key factor driving the growth of the yellow fever vaccines market share is the growing demand of products in routine immunization & travelers one of the major reasons to drive the market. Rapid urbanization developments will further boost the overall market.

KEY INDUSTRY PLAYERS

Leading Manufacturers to Boost Product Demand

Study includes information on the market players and where they stand within the sector. Data is being collected and made available through proper research, mergers, technical advancement, growing production facilities, and cooperation. The study on materials offers details on manufacturers, regions, types, applications, sales channels, distributors, traders, dealers, research findings, and more.

• Sanofi Pasteur: According to company data, Sanofi produces over 20 million doses of yellow fever vaccines annually, making it a global leader in supply.

• Bio-Manguinhos (Brazil): As per the Brazilian Ministry of Health, Bio-Manguinhos supplied 54 million vaccine doses between 2020–2023, meeting domestic and export demand.

List of Top Yellow Fever Vaccines Companies

• Sonofi Pasteur (France)
• Bio-Manguinhos (Brazil)
• Institute Pasteur de Dakar (U.S.)
• FSUE Chumakov (Russia)

REPORT COVERAGE

The study goes into great detail about market segmentation by type and application. The study examines a broad range of participants, including existing and potential market leaders. A considerable market expansion is anticipated as a result of several important factors. In order to provide market insights, the research additionally analyses elements that are probably to boost yellow fever vaccines market share. The report makes forecasts for market expansion during the projected time period. The objective of the regional study is to explain why one region dominates the worldwide market. There are a lot of issues that have all been carefully considered that prevent the industry from growing. The research also contains a market strategic analysis. It includes thorough market information.