Serine Market Size, Share, Growth, and Industry Growth By Type (L-Serine, D-Serine and DL-Serine) By Application (Pharmaceutical, Food, Cosmetics and Others), Regional Insights and Forecast To 2033

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SERINE MARKET OVERVIEW

The serine market, valued at USD 0.28 billion in 2024, is forecasted to grow consistently, reaching USD 0.3 billion in 2025 and ultimately hitting USD 0.32 billion by 2033, at a steady CAGR of 5.4% from 2025 to 2033.

Serine is an amino acid, which is one of the building blocks of proteins. It is a non-essential amino acid, meaning that the body can synthesize it on its own, but it can also be obtained from dietary sources. In addition to its role in protein synthesis, serine also plays a key role in several metabolic pathways in the body. For example, it is involved in the biosynthesis of other important compounds, such as phospholipids and purines. Serine is also a precursor for the production of the neurotransmitter glycine, as well as the amino acid cysteine. Serine is considered a "conditionally essential" amino acid, meaning that in certain situations, the body may require higher levels of serine than it is able to produce on its own. For example, during periods of growth and development, or during times of illness or injury, the body's demand for serine may be increased.  

KEY FINDINGS

COVID-19 IMPACT 

The Disruption of the Supply Chain Had an Effect on Market Value  

The COVID-19 pandemic has disrupted supply chains and led to temporary closures of some manufacturing facilities, which could potentially affect the production and availability of serine and other amino acids. Additionally, the pandemic has led to changes in consumer behavior, with many people increasing their consumption of dietary supplements and other health-related products, which could drive up demand for serine and other amino acids.

LATEST TRENDS

Growing Demand for Serine in the Food and Beverage Industry to Drives Market Growth 

Serine is gaining traction in the food and beverage industry as a functional ingredient that can improve texture, flavor, and nutritional content of various products. The rising demand for healthier and natural food ingredients, coupled with the increasing popularity of plant-based diets, has fueled the demand for serine as a versatile amino acid that can be derived from both animal and plant sources.  

• Global serine production surpassed 6,300 metric tons in 2023 due to increased demand from the nutraceutical and cosmetic industries.

• Biotech-derived serine accounted for 41% of total output in 2023, reflecting a shift from synthetic methods to microbial fermentation.

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SERINE MARKET SEGMENTATION

By Type

By type, the serine market is segmented into L-Serine, d-serine, and dl-serine.

The d-serine segment will dominate the serine market in the coming years. 

By Application

Based on applications, the serine market is pharmaceutical, food, cosmetics, and others.

The pharmaceutical use segment will lead the global share through 2033. 

DRIVING FACTORS

Growing Popularity of Health and Fitness Trends to Fuel Market Growth 

 The market for serine is being driven by a variety of factors, including the increasing popularity of health and fitness trends. As more consumers seek to improve their overall health and wellbeing, they are turning to a range of nutritional supplements, including amino acids like serine, as a way to support their goals.

Growing Consumer Awareness of the Health Benefits of Amino Acids will Drive Market Growth 

As more research is conducted on the various health benefits of amino acids like serine, consumers are becoming more aware of the potential advantages of incorporating these nutrients into their diets. This is driving demand for serine and other amino acids as dietary supplements and functional ingredients. 

• According to national food safety authorities, serine was used in the formulation of over 2,100 amino acid supplements distributed in 2023.

• In 2023, demand for serine in skincare applications rose by 29%, driven by its role in enhancing hydration and barrier repair.

RESTRAINING FACTORS

High Production Costs and Limited Availability of Raw Materials Pose Challenges for Market Growth

Serine is a relatively expensive amino acid to produce, and the high costs associated with its production and processing can limit its commercial viability and accessibility. The primary raw materials used in serine production are animal and plant-based proteins, which can be subject to supply chain disruptions and price fluctuations. This can impact the availability and cost of serine as a functional ingredient or dietary supplement.

• The average export price of serine increased by 18% year-on-year in 2023 due to raw material supply volatility.

• Over 37% of small-scale manufacturers faced compliance challenges linked to purity standards and bio-based certification processes.

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SERINE MARKET REGIONAL INSIGHTS

Asia Pacific to Grow at the Highest Serine Market Share During the Forecast Period 

Asia Pacific is a major producer and consumer of serine, driven by the large-scale production of animal and plant-based proteins in countries like China and India. The region is also home to a growing number of health-conscious consumers, who are driving demand for serine as a dietary supplement and functional ingredient in food and beverage products.

 North America is a mature market for serine, with well-established players and a strong regulatory environment. The region is home to a large number of food and beverage companies that use serine as a functional ingredient, as well as pharmaceutical and cosmetics companies that value serine for its therapeutic and skincare benefits.

KEY INDUSTRY PLAYERS

Key Players Focus on Partnerships to Gain a Competitive Advantage

Prominent market players are making collaborative efforts by partnering with other companies to stay ahead in the competition. Many companies are also investing in new product launches to expand their product portfolio. Mergers and acquisitions are also among the key strategies used by players to expand their product portfolio. 

• Ajinomoto produced more than 1,750 metric tons of pharmaceutical-grade serine in 2023, primarily for neurological and metabolic disorder treatments.

• Evonik expanded its fermentation-based amino acid line with a serine variant in 2023, enabling supply to over 40 industrial clients across 17 countries.

List of Top Serine Companies

• Ajinomoto (Japan) 
• Evonik (Germany)
• KYOWA (Japan)
• Mitsui Chemicals (Japan)
• Amino (China)
• Wuxi Jinghai Amino Acid (China)
• Apeloa (China)
• Bafeng Pharmaceutical (China)
• Jiahe Biotech (China)
• Hua Yang Chemical (China)

REPORT COVERAGE

The market research study examines the worldwide market in detail, focusing on important elements such as leading players, product/services, or type, and leading end-use applications. Aside from that, the research analyses major advancements and provides insights into lighting market trends. In addition to the causes indicated above, the paper includes several other factors that have contributed to serine market growth in some regions.