Serine Market Size, Share, Growth, and Industry Growth By Type (L-Serine, D-Serine and DL-Serine) By Application (Pharmaceutical, Food, Cosmetics and Others), Regional Insights and Forecast From 2025 To 2035

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SERINE MARKET OVERVIEW

The global serine market size stood at USD 0.3 billion in 2025 and is projected to reach USD 0.32 billion in 2026, growing further to USD 0.36 billion by 2035 at an estimated CAGR of 5.4% from 2025 to 2035.

Serine is an amino acid, which is one of the building blocks of proteins. It is a non-essential amino acid, meaning that the body can synthesize it on its own, but it can also be obtained from dietary sources. In addition to its role in protein synthesis, serine also plays a key role in several metabolic pathways in the body. For example, it is involved in the biosynthesis of other important compounds, such as phospholipids and purines. Serine is also a precursor for the production of the neurotransmitter glycine, as well as the amino acid cysteine. Serine is considered a "conditionally essential" amino acid, meaning that in certain situations, the body may require higher levels of serine than it is able to produce on its own. For example, during periods of growth and development, or during times of illness or injury, the body's demand for serine may be increased.  

KEY FINDINGS

COVID-19 IMPACT 

The Disruption of the Supply Chain Had an Effect on Market Value  

The COVID-19 pandemic has disrupted supply chains and led to temporary closures of some manufacturing facilities, which could potentially affect the production and availability of serine and other amino acids. Additionally, the pandemic has led to changes in consumer behavior, with many people increasing their consumption of dietary supplements and other health-related products, which could drive up demand for serine and other amino acids.

LATEST TRENDS

Growing Demand for Serine in the Food and Beverage Industry to Drives Market Growth 

Serine is gaining traction in the food and beverage industry as a functional ingredient that can improve texture, flavor, and nutritional content of various products. The rising demand for healthier and natural food ingredients, coupled with the increasing popularity of plant-based diets, has fueled the demand for serine as a versatile amino acid that can be derived from both animal and plant sources.  

• According to the World Health Organization (WHO), over 462 million people are underweight globally as of 2021, driving the use of amino acids like serine in dietary supplements to address malnutrition.

• The U.S. National Institutes of Health (NIH) reports that over 7,000 rare diseases are under study, with amino acids such as serine being tested in metabolic and neurological disorder treatments.

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SERINE MARKET SEGMENTATION

By Type

By type, the serine market is segmented into L-Serine, d-serine, and dl-serine.

The d-serine segment will dominate the serine market in the coming years. 

By Application

Based on applications, the serine market is pharmaceutical, food, cosmetics, and others.

The pharmaceutical use segment will lead the global share through 2035. 

DRIVING FACTORS

Growing Popularity of Health and Fitness Trends to Fuel Market Growth 

 The market for serine is being driven by a variety of factors, including the increasing popularity of health and fitness trends. As more consumers seek to improve their overall health and wellbeing, they are turning to a range of nutritional supplements, including amino acids like serine, as a way to support their goals.

Growing Consumer Awareness of the Health Benefits of Amino Acids will Drive Market Growth 

As more research is conducted on the various health benefits of amino acids like serine, consumers are becoming more aware of the potential advantages of incorporating these nutrients into their diets. This is driving demand for serine and other amino acids as dietary supplements and functional ingredients. 

• As per the Food and Agriculture Organization (FAO), global livestock production has grown to provide 40% of world agricultural output, increasing the use of serine in feed additives for protein synthesis.

• According to the International Federation of Pharmaceutical Manufacturers & Associations (IFPMA), over 50% of new drugs in development rely on amino acids as intermediates, supporting serine’s adoption.

RESTRAINING FACTORS

High Production Costs and Limited Availability of Raw Materials Pose Challenges for Market Growth

Serine is a relatively expensive amino acid to produce, and the high costs associated with its production and processing can limit its commercial viability and accessibility. The primary raw materials used in serine production are animal and plant-based proteins, which can be subject to supply chain disruptions and price fluctuations. This can impact the availability and cost of serine as a functional ingredient or dietary supplement.

• According to the U.S. Department of Energy (DOE), the cost of producing biochemicals like serine via fermentation can be 20–30% higher compared to synthetic chemical processes, limiting scalability.

• The World Bank states that over 700 million people lived in extreme poverty in 2021, restricting affordability and demand for specialty amino acids such as serine in low-income regions.

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SERINE MARKET REGIONAL INSIGHTS

Asia Pacific to Grow at the Highest Serine Market Share During the Forecast Period 

Asia Pacific is a major producer and consumer of serine, driven by the large-scale production of animal and plant-based proteins in countries like China and India. The region is also home to a growing number of health-conscious consumers, who are driving demand for serine as a dietary supplement and functional ingredient in food and beverage products.

 North America is a mature market for serine, with well-established players and a strong regulatory environment. The region is home to a large number of food and beverage companies that use serine as a functional ingredient, as well as pharmaceutical and cosmetics companies that value serine for its therapeutic and skincare benefits.

KEY INDUSTRY PLAYERS

Key Players Focus on Partnerships to Gain a Competitive Advantage

Prominent market players are making collaborative efforts by partnering with other companies to stay ahead in the competition. Many companies are also investing in new product launches to expand their product portfolio. Mergers and acquisitions are also among the key strategies used by players to expand their product portfolio. 

• Ajinomoto: According to company disclosures, Ajinomoto produces amino acids, including serine, in 30+ manufacturing sites worldwide, with applications across food, feed, and healthcare sectors.

• Evonik: As per industry data, Evonik operates in over 100 countries and produces high-purity serine for pharmaceutical and industrial applications, supported by its over 33,000 employees globally.

List of Top Serine Companies

• Ajinomoto (Japan) 
• Evonik (Germany)
• KYOWA (Japan)
• Mitsui Chemicals (Japan)
• Amino (China)
• Wuxi Jinghai Amino Acid (China)
• Apeloa (China)
• Bafeng Pharmaceutical (China)
• Jiahe Biotech (China)
• Hua Yang Chemical (China)

REPORT COVERAGE

The market research study examines the worldwide market in detail, focusing on important elements such as leading players, product/services, or type, and leading end-use applications. Aside from that, the research analyses major advancements and provides insights into lighting market trends. In addition to the causes indicated above, the paper includes several other factors that have contributed to serine market growth in some regions.